1) When the Facebook people change their layout and competely screw it up AGAIN! Welcome to the land of it is never going to work properly.
2) Something that is screwy or fucked-up.
3) Someone who updates their Facebook status while drunk.
Dear Facebook, how can this possibly be the most recent news feed when it is from an hour ago? And the Top News is from 14 hours ago, and I didn't see it until now. Dude, you are all FBed-up!
or

New Facebook bites big bologna! It is all FBed-up!
or

You were so wasted last night! Your status updates were all FBed-up!
by edits451 February 09, 2010

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