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2. F.F.S.
stand for For F#$$ SAKES. Used in Online Games Such as CoH CoV WoW
F.F.S. I got Pwned!
F.F.S. There are way to many bosses here.
1. F.F.S.
For Fuck's Sake

Originally used in Quake, created and defined by team OLD
(The Mike's)
You just got 'naded by a spammer.

A common reply to this might be:
F.F.S.