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1.
The result of when someone tells you something highly unbelievable, or just plain surprising. It can also be used elsewhere, such as when you're dissed. Basically a vulgar form of excuse me.
(while watching South Park on tv)

Ms. Garrison - "So there you go! You're the retarded offspring of five monkeys having butt sex with a fish-squirrel! Congratulations!”
Me - Ex-the-fucking-scuse-me?
by southpark948 September 03, 2007