A combination of both Ebola and AIDS.
Ebola makes you vomit your own blood and AIDS ruins your immune system and both are highly contagious.
So basically, you puke poisonous blood.
You WILL be under quarantine for the rest of your life.
You shouldn't need an example, it's pretty easy to understand
"Father, I think I have Ebola AIDS." *vomits blood into sink*
"Son, you are quarantine."
*Son in hospital*