Top Definition
When a person becomes overly obsessed about a game/series that not too many people cared about, until it was brought back from another popular series, either through reference, re-ports, or in-game demo(s). (Gaming is not the only restriction to this disease, as it can work for shows, or musical artists as well, should the definition fit this situation.) This produces an "unrealistic" fanbase that would not have existed in the first place, had the game/character never appeared as a selectable choice in the first place. (Taking gaming as an example.)

Another example/series includes Phoenix Wright. The game was originally released for the Game Boy Advance back in 2001. It was never translated or cared about too much in the United States, until it was re-released in 2005 for the Nintendo DS. Only then did people start wearing blue, formal attire to gaming conventions shouting "OBJECTION!" every time.
Recently, even "Osu!" has been receiving this illness.
Look at the definitions written for 'EarthBound' and tell me how they're NOT experiencing EarthBound Syndrome. The poor souls.
by the dude that walks September 22, 2010
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