In the jargon of Magic: The Gathering, EOTFOFYL is an acronym for "End of turn Fact or Fiction, You lose". Fact or Fiction is an extremely powerful card in the game, when played properly it can win games almost instantly.
Jon Finkel: Okay, I play Chimney Imp and end the turn.
Mike Long: WAIT GODDAMIT
Mike Long: EOTFOFYL
Jon Finkel: O SNAP