Top Definition
The acronym for the popular cartoon "Ed, Edd n' Eddy"
Me: "Have you ever noticed on EEnE that Eddy has tissues next to his bed?!"
Other fan: "...yes?" o.O
Me: "LOL it means he masturbates. It's an inside joke, get it?!" :D
Other fan: "You're sick."
Me: "I know" :P
EEnE hater: "EEnE sucks balls!!!!!!"
Me: "DIIEEE!!" *shoots the hater*
by EEnE fanatic June 05, 2008

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