look up any word, like dirty sanchez:
 
1.
E45
An online variant of the P45 form (collected when a person leaves work permanently).

It is used when a person chooses to rescind their friend status with another person.

Alternatively, one may have their friend status rescinded because of behaviour which is deemed unacceptable.
Hey, pick up your E45 you are no longer my e-pal / friend / buddy.

Fuck you, I'm gonna collect my E45, I'm not gonna put up with you Sean.
by roffle iron September 03, 2008
 
2.
E45
a hard hand job lubricated with E45 moisturising lotion.
gimme a E45, gewww i got the hard time init.
by Yon Yon August 22, 2009