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What you tell a person you are having a serious conversation with when they try to trivialize the discussion topic by interrupting you the informal pronoun dude.
Sample Conversation...
Jim says, "John, you need to show your mother a little more respect."
John replies,"Dude?" (as in dude are you serious?)
Jim replies, "Dude. Don't dude me!"
by Dre March 01, 2005

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