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A loose women that will ride any man who has drugs.
That Sadi is a ho, fuckin' drugstore cowgirl.
by Jimmydeansausage4treal January 19, 2009
Someone with an addiction or severe medical condition that requires copious amounts of prescription medication. It applies to legit and illegal prescriptions.
I know a Drugstore Cowgirl, so afraid of getting bored. She's always running from something. So many things ignored"--Lyrics to 311's "Beautiful Didaster
by Joscel June 22, 2011