A period of 2 or more days of consistent use of illegal narcotics (e.g. weed, pills, speed, MDMA, mephadrone, cocaine, 2CB etc) without sleep. Normally (but not always) with a combination of drugs to try and stabilize the upper/downer effect - therefore maximizing the length of the binge. Often participants will consume large amounts of alcohol but never seem to get drunk due to effects of all the drugs.
"Hey dude, you don't look too good."
"Yeah I feel like shit, been on a 4 days drug binge. It was awesome!"