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1. Drapetomania
Drapetomania is a term that derived in the slave days and was used to describe the "disease" in which the symptoms were "a slave that was addicted to attempting escape or escaping slavery..."

Cure: cut off their toes.
None needed.
2. Drapetomania
The overwhelming urge to run away.
I'm sick of this city, Drapetomania is taking me over.