Top Definition
A tasty blend of Dr. Pepper or Mr. Pibb mixed with Slice made by PepsiCo until discontinued in early 2006 and replaced by Cheerwine. Dr. Slice had the magical effect of producing an unbreakable smile after 60 oz. and anal urination after 80 oz. Dr. Slice had a seemingly unconquerable limit of consumtion of 100 oz. in 1 hour, which was later found to be false by the biggest and strongest men: Mark and Kyle.
I've been to a lot of doctors, but only one doctor has made it possible for me to piss out of my butt: Dr. Slice!
by Dustin Swimmer July 14, 2006

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