22
Another name for your Nintendo DS is Down Syndrome.
Brian: Hey dude do you have your Down Syndrome today?
Kevin: Yea i have my Down Syndrome and i brought golden eye for multi player.
Brian: Sweet.
Kyle: What the hell is a Down Syndrome?
Brian: Jesus Christ Kyle it's a DS.
Kyle: Oh
Audie: Shut up hoe!
Mug icon

Dirty Sanchez Plush

It does not matter how you do it. It's a Fecal Mustache.

Buy the plush
23
very strange...and exessively weird
cara is the coolest kid with down syndrome i know
by ilovematthew May 08, 2006
Mug icon

Cleveland Steamer Plush

The vengeful act of crapping on a lover's chest while they sleep.

Buy the plush
24
A phrase used to make fun of someone after they have done something stupid. Also, a disease similar to mental retardation. Many people who have down syndrome have competed in the Special Olympics.
What the hell is your problem! Are you down syndrome or something?
by J-dog April 09, 2005
Mug icon

Cleveland Steamer Plush

The vengeful act of crapping on a lover's chest while they sleep.

Buy the plush
25
A tragic mental illness some kids are born with. It makes them mentally retarded and physically deformed. It is in a word something neither the parents nor the damaged child should have to go through as it places an extra heavy burden on the parents and denies the child the chance he/she deserves at life.
My son was born with down syndrome. I still love him though

Paul Gowland got his ass kicked by that kid with down syndrome. He shouldnt be picking fights with a kid like that.

The world would be a better place without down syndrome
by itsadamnshame March 22, 2010
Mug icon

Dirty Sanchez Plush

It does not matter how you do it. It's a Fecal Mustache.

Buy the plush
26
an insult, to say to ones friends when they are acting 'crippled'
Clutch, are you fuckin down syndrome!
by 106_joN March 27, 2005
Mug icon

Golden Shower Plush

He's warmer than you think.

Buy the plush
27
Another name for opiate junkies who are nodding out on the shit. Often so retarded/out of it that they manage to light themselves on fire smoking heroin off of tin foil, or when they fall asleep smoking.
Dude 1: "Hey, what's wrong with that guy over there? He's sleeping and drooling all over himself, and his cigarette is so close to that pile of flammable magazines..."
Dude 2: "Oh, that's just Derek. He's got Down syndrome. Every time he gets paid he buys oxycontins."
by westernclassics October 13, 2009
Mug icon

The Urban Dictionary T-Shirt

Soft and offensive. Just like you.

Buy the shirt
28
That stage in the night at which you've had too much to drink, partied too hard, danced too much, or drank that one spirit that really puts you on a downer. The syndrome can often be amplified if the patient is going through some sort of trauma or difficulty in his or her (sober) life. The sufferer will also attempt to start deep, meaningful conversations with friends or even unknown passers by, spilling out his or her emotions in an attempt to solve his or her problems. This is usually followed by regret the next morning.
some are more prone than others.
Robert: Hey, why's Joe slumped in his chair, not talking to anyone, on his phone (again)?
Laura: ooohh...yeah I forgot to tell you something about Joe...he's got Down Syndrome. Stay well clear of him.
by joeiles August 31, 2008
Mug icon

The Urban Dictionary T-Shirt

Soft and offensive. Just like you.

Buy the shirt