a.) Derived from "Dopamine Reuptake Inhibitors", is slang for cocainebecause it has the notorious effect of a Dopamine Reuptake Inhibitor: stimulant rewards and drives like euphoria, orgasm, anger, addiction, love, and pleasure.

b.) Also used to describe something positive and or prodigious as to compare to a DARI(Dopamine Reuptake Inhibitor):cocaine and crack cocaine.
a.) From 1984 and 1990 dope was at its prime.

b.) Reasonable Doubt was a total classic with super dope production.
by a Washington, D.C. resident January 25, 2009
Sick, Extremely Nice
Man, did you hear that new Juice song... It was Dope!
by Anonymous September 15, 2003
In the urban southeast and other areas: crack cocaine.
"He went from soft to being a dope fien"

Eminem: "How his mom is a dope addict, and his ex-wife how they go at it." - Encore
by Ali J December 20, 2004
n. any powder, rock, or meth-based drug

adj. mad phat, yo.

v. to drug
n. Is eight grams of dope alright, Mr Bush?

adj. Dope rims, yo.

v. Dope him up and grab his balls!
by deathtobees December 19, 2003
Although Dope is not an Adj., it is somehow used as one, meaning "cool" or "Good"
" oh man, these colors are so dope"
"dope is not an Adjective you dumbass hippie, go to hell"
by Kestrel July 22, 2005
That is cool
A word for drugs on the street
That dope we had last night was dope.
Lets get some dope from the city
That outfit is dope
by velina December 12, 2003
A shortened derogatory term for "dopey"
"You are a complete and utter dope!"
by xpdamus June 24, 2005

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