Pot-head (In refrence to Coke): "Hey man, I ain't never ganna touch no Dope"
Coke-Head (In refrence to Heroin): "Man, that moron Jimmy is dippin' into that Dope again"
People who do Marajuanna call Heroin Dope.
Word has also been used to describe how good somthing is.
OMG, I smoke the green but I don't do dope ( AKA Heroin )
Man that car is dope!