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1.
A phrase often used by computers and robots in science fiction TV shows and movies, meaning failure to understand.

The phrase has been attributed to the comedy TV show ‘My Living Doll’.
Does not compute. Please say that again in plain English.
by AuntyMouse April 12, 2009
 
2.
Robot slang for "I don't know" generally followed by an exploding head.
"does not compute, does not compute... *BOOM*"
by nate-dawg-dizzle December 07, 2009