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1.
When a woman is licking a man's asshole and he farts while she is performing said act.
"I will never lick his ass again because he gave me a Dirty Cupcake!"
by Tim/Brit May 11, 2010
 
2.
Oakland/San Francisco-based all-girl punk band
Are you going to Dirty Cupcakes' next show? Duh.
by Dirty Cupcakes Is A Band March 02, 2011