Top Definition
A lozenger to sooth the asshole within and make said asshole calm down. Similar to a lozenger to sooth a sore throat.

Cure for someone being an asshole. To be used to restore said asshole to a normal state of being. Triple strengh maybe required for stubborn or resistant assholes.

Keep a pack handy for you are having a great time and some prick comes in and spoils the mood.
"Hey man, what the fuck is wrong with you? Take a Diffahole and chill."

"What an asshole, he needs to take a pill. Give him a Diffahole."
by Krazy Kreations September 23, 2011

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