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When someone who is so crazy, they have lost their marbles. Can refer to very stressed people, random people, and truly insane people.
Person1: Oh my fucking god, did you see that man walking down George Street NAKED?!
Person2: Yeah, he was freaking de-marbled!
by TheDictionaryQueen August 29, 2009

Words related to De-Marbled

crazy insane mad nuts random