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2.
Suffering from being the less attractive older sibling
Person 1: Whoah Jenn is so much hotter than her older sister..what happened?
Person 2: Dakota Fanning Syndrome bro..
by f0xycleopatra October 02, 2012
 
1.
The bodily ailment that causes a person to reflect a much younger age than their actual numbers of years shows.
Examples of DFS, "Michael Cera has got the worst case of Dakota Fanning Syndrome that I've ever seen.", "Hasn't Dakota Fanning been six for like, 10 years?"
by DGAFalot June 22, 2010