Basically a euphuism for semen.
*Two dudes are chillin in a bar and sippin on some brewskis*
Dude 1: Who were you talking to just now...wasn't that Isabelle?
Dude 2: Yeah it was Isabelle the hot French chick
Dude 1: Woah dude...she's really hot!
Dude 2: That she is. You know what would make her even hotter?
Dude 1: What?
Dude 2: My daddy cream all over her face....ha ha!
Dude 1: Damn dude...you can be such a mofo sometimes. But on some real talk I'd do it too if she let me!
*Both continue to sip beer and check out the chicks*