DU
Commonly-used, abbreviated form of Delta Upsilon, the first non-secret fraternity, currently the world's only international non-secret, non-hazing fraternity. North America's fifth oldest fraternity, it was founded at Williams College, Mass in 1834.

It is also currently Canada's largest fraternity with 5 chapters. Commited to Building Better Men, Delta Upsilon's non-secrecy allows it to be held accountable to its four founding principles, the development of character, the promotion of friendship, the diffusion of liberal culture, and the advancement of justice.

Dikaia Upotheke, Justice our Foundation
I rushed DU, because I don't see the point of keeping a fraternity's values and rituals a secret.
by D_$ September 23, 2007

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Top Definition
When something really lame occurs, one may exclaim "D.U."
"D.U. Look at that drunken construction worker piss on himself."
by stink-foot January 15, 2007

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DU
DU(Drunks united) was started on October 15, 2006 by Thomas G from Smithtown High School. Immediately members flocked to DU marking the start of DU as we know it today. Later, three unusually slutty women(ranging from 130-450 lbs), joined followed by a junior at the time. Two months later these ladies were dropped from the group. DU has a total penis length of 250 feet, and is ethnically 83% white and 17% nazi. A negligible percent are asian.
"Wow that one kid in DU is fucking retarded."
by Roger Shankar December 03, 2006

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du
A contracted form of the word dude. In the same way foo is the shortened version of fool.
What's up du?

Oh...come on du, hurry up!
by Aberwyvern February 23, 2005

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Du
Do and you combined
Du have any chocolate?
Du want a hand?
Du like ice-cream?
by Nix AKA the almighty June 16, 2014

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fellatio; blow job; oral sex performed on a male; acronym for "drink up"
Male: Ayo shorty when Imma get that D.U.!
Female: You got me twisted! I don't put my mouth on nothin!
Originated at Lincoln University in Missouri
by izwhateva July 18, 2010

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Acronym - Dangerous Underpants Situation
This is my last clean pair! D.U.S!
by Sam Parsons February 08, 2004

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du'
compadre, amigo, friendly folk, compa,
dude spoken with a trailing, marijuana-influenced accent. (Valley Sheep Talk)
This shi' is hella tight du'
by LeRoy Mambeaux November 13, 2003

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