Top Definition
Down To Fuck Shit Up

i.e. crash a party or wreck a party (in a good way or destructive way)
John: Hey man, there's a sick triple kegger at my friend's place with 40 sorority chicks. You DTFSU?
James: HELL YEA! Lets get some tonight!
by Roomie#3 December 09, 2009
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