look up any word, like the eiffel tower:
 
2.
DPE
stands for Delta Phi Epsilon, a Professional foreign service fraternity and sorority originated at Georgetown University. Also active at George Washington University and UC Berkeley. Not to be confused with the social sorority, Delta Phi Epsilon which refers to itself as D Phi E.
"DPE is hosting a professional event tonight with the Ambassador to Pakistan"
by beebop912 February 03, 2008
 
1.
DPE
DPE is an acronym for Designated Pussy Eater.

pronunciation /Dee-Pee-Ee/ (noun) : One who gives oral stimulation to a woman's vagina with no other forms of sexual contact. A DPE cannot give or receive any other sort of sexual contact.
Kyle went down on Sarah twice yesterday, and nothing in return. He is her DPE.
by TonyR69 April 20, 2010