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1.
Acronym for "Don't Douche It Up"

Meaning, don't inject your own special brand of doucheness into anything you don't want fucked up.
Happy Tuesday - just remember, when it comes to your day today, DDIU...

Good luck in the interview, man...DDIU.

If you want everything to work out, then DDIU, dude.
by Jimmy from the Ville September 06, 2011