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1. D.T.F.
Acronym for "down to fuck."
All the hoes in this party are D.T.F.
2. d.t.f.
down to fuck

trying to hook up, and/or have sex.
drunk stephen: yo boo, d.t.f.?
random girl: d.t.f.?
drunk stephen: yeah boo, you down to fuck?
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