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To not win the World Series in 100 years.
See also: Epic Fail, and Pwned.
Guy 1: Doesn't seem like the Braves are going to win the World Series for a while.

Guy 2: Must be Cub's Syndrome.
by $lim $hady October 19, 2008

Words related to Cub's Syndrome

epic fail world series 100 years braves cubs pwned suck