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1.
Crucio is another of the 3 'Unforgivable Curses' from Harry Potter by J.K. Rowling.

The Cruciatus Curse is used to inflict agonising pain on the victim and will land you a spell (no pun intended!) in the Wizard Prison'Azkaban'

This curse was used to permanently damage Neville Longbottoms parents mental capacity whilst under interrogation/torture by Bellatrix Lestrange and Co.
"So, you won't speak...maybe this will loosen your tongue...CRUCIO!"
by Dumbledore July 27, 2004