A person so nuts or "ape-shit crazy" that they disturb peace, daily life, and very possibly the very fabric of the universe.
OMFG! Mrs. Puttana is such a crazy ass mother fucking bitch for giving us a eighteen page essay over Winter break! How I am supposed to enjoy my childhood like this?!
Stupid Crazy Ass Bitch Syndrome (SCABS) is an extremely common disorder in females. SCABS infects more than 95% of females over the age of 43. Symptoms include idiocy, delusion, irritability, and overall extreme cuntish behavior. A woman with this syndrome is called a 'SCAB.' Unfortunately, SCABS can cause irritation, emotional distress, marital problems, and, in extreme cases, psychosis in the spouse or significant other.
My wife has a chronic case of Stupid Crazy Ass Bitch Syndrome (SCABS). She is just like a bloody real scab, the longer it's around the uglier it gets.