Top Definition
A girl who is self-righteous, self-centered, selfish and obsessive.
Crazy Bitch Syndrome is a defined as girl who gets mad at you for looking at her facebook and you see she is cheating on you but feels looking at her facebook is a "breach of trust".
A girl who calls you selfish for breaking up with her has CBS.
A girl who says she trusts you but wont let you hang out with girls.
A girl who wants to get married as soon as possible so you wont leave her because she is afflicted with Crazy Bitch Syndrome.
by Kava'Cre March 01, 2011

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