Crusty and Ankles being compounded into one word.
Somebody with a unusual amount of crust on their ankles.
Eww look at Theleah she has crankles!
Crankles: unusually skinny, bony ankles, which in comination with other observable traits, may indicate habitual use of methampetamine, also known as crank. A "crank skank", for example, would likely have crankles. Derived from the term "cankles" - its opposite.
"Check out the crankles on that ho!; bet she'll fuck me for this fuckin' phat rail!"
Crease left in your ankle by socks or tapered pants. Not to be confused with Cankles
Damn son your socks are too tight, you got mad crankles
The condition which usually afflicts large ladies where the ankle and calf are nearly the same diameter
When you're cranky, and grumpy, and are just flat out pissy.
"Oh my god, she's got a bad case of the crankles!"
A person that gets inured easily, and constantly hurts themselves.
"I landed on my ankle playing basketball today."
"Yo, you're such a crankle!"