Top Definition
What you say when someone says or does something stupid.
Originally seen on Football Night in America.

Can be elongated or stretched out if quote/action is incredibly stupid. i.e. cooommmme oooonnnn, mmaaaaannnnn.
Tim: "Do you think that coke machine accepts pennies?"
Me: "Come On, Man."

Jeff: *playing basketball, shoots an airball when his teammates were open.
Teammates: "Come On, Man!"
by cline26 May 31, 2010

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