Top Definition
A game played by two people (generally both male) involving a tube of any brand mint tooth paste and several cans of coke (at least 12). The game is played by first holding a medium amount of toothpaste in your mouth at full strength for as long as you can stand the minty burn. After 20 seconds, you spit it into a cup and take a big swig of Coke. This produces a horrible taste in one's mouth and is the object of the game: Who can last longer with that horrible combination. The winner if the one who does NOT give up.
"Me and Chris played Coke and Toothpaste last night, and screwed up the carpet in his room pretty bad when he puked..."
by Zeto, the DUNE Fanatic March 16, 2005
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