Can mean sexually or simply speaking with.
If you wish to speak to a woman, and she is currently speaking with another man, she is said to be cockupied.
NOTE: The other definition listed here should be classified as "Precockupied"
I told you this shit was wack! Let's go to da club! Der be da freaks!
Ahh shucks Dick, she's cockupied by that asshole Donald!
Phil: "Hey, where's Rob? I thought he said he be here tonight."
Jerry: "Yeah, he did. But he met a cute girl at the bar and wouldn't leave."
Phil: "That Rob, he's always cockupied..."
Jack (waiting in line for the bathroom after a long night at the bar with a friend): "Hey man, you still cockupied in there or can I take a leak??"
The urologist had a long day at work after being consistently cockupied for 8 straight hours.
brodeo, sausage fest, meat convention- these are all places/events that would be described as cockupied.
Derd 2: "Ok, but we're not going to Squirrel's house again. It's useless. That dude's parties are always just cockupied."