Referring to a person or group of people who are exceptionally drunk and/or under the influence of a large amount of drugs, which causes a huge decrease in their decision making abilities; usually resulting in terrible choices which one would immediatley regret upon becoming sober.
Dan: Holy shit dude what happened to you last night?
Jon: Bro, I got so Chris drunk last night I banged that fat girl fromthe bar...
Dan: Yeah, but didn't you already banged her last week?? What's the big deal now?
Jon: Well last night before we fucked she told me she had herpes and she was falling in love with me...
Dan: Well what did you say??
Jon: "Let's fuck"
Dan: Wow dude, you were seriously Chris drunk last night...
Jon: I know bro, I know... I'll call you later, I gotta go meet this fat sluts parents and stop by CVS to pick up my prescription... ugh.