Top Definition
An ultra-popular FPS series that (in the minds of some) is so addictive, that it can often lead to many cases of negligence towards loved ones. This often results in divorces - which is ironic, considering that the abbreviation for the Call of Duty series is 'CoD' - the same as 'Cause of Divorce'.
Gamer 1: "Hey, want to play some cee-oh-dee?
Gamer 2: "Sorry, but if I played that game again, the missus would murder me to hell."

That scene demonstrates the obscenely powerful, lasting effect of Cause of Divorce (Call of Duty).
by MintagedVortex January 09, 2011

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