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1.
Portmanteau of "cash" and "astigmatism". The ailment of being rendered either short-sighted or blind due to dollar signs in the eyes. A level of greed that results in a person behaving without thought to future consequences. First used in Jeph Jacques' webcomic "Questionable Content".
Faye: I only have to pay a third of the rent instead of half! There are dollar signs dancing in my eyes!
Dora: Careful, our eye-care plan doesn't cover cashtigmatism.

Did you hear? John inherited a bunch of money from his uncle, but it gave him cashtigmatism and he blew it all on silly putty and gummi bears.
by Astrolounge January 18, 2010
 
2.
The medical condition wherein the United States dollar sign is visible in the human eye.

Credit: J. Jacques
(questionablecontent.net)
Faye: "I only have to pay a third of the rent instead of half! There are dollar signs dancin' in my eyes!"

Dora: "Careful, Faye. Our eye-care plan doesn't cover cashtigmatism."
by Dexi January 18, 2010