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1.
An adjective used to describe someone who is extremely arrogant and/or overbearing, with grandiose ideas about themselves, but little clue as to how ridiculous and self-inflated they look.
Taken from the Cardassian race from Deep Space 9.
Guy 1: God, Fletcher Daniels is such a Cardassian.
Guy 2: I know. Did you see him hitting on Patsy? What a dick.

Guy: Why are you being such a Cardassian today?
by Lunettarose December 12, 2008
 
2.
A Star Trek alien species native to Cardassia Prime.
Gul Dukat is a cardassian
by Walking Talking Dictionary September 25, 2006