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5.
Someone who fucks cadavers. Stemmed from the phrase mofo. A mofo is a motherfucker, and a cafo is a cadaver fucker. A cadaver is a dead body. The A is pronounced like in "cafe" or like in caffienated. But not quite. Because this is cafo. Not caffienated. Duh.
"God, what a cafo!"

"Eww, you're such a cafo."

"Guess what? I just heard that MEG MALM is a CAFO."
by Meg Malm Is A Cafo January 07, 2005
 
1.
Concentrated (or Confined) Animal Feeding Operation, also known as a 'factory farm'. In industry/government publications, CAFO will usually signify "Concentrated". Many non-industrial organic farmers and animal rights advocates prefer "Confined" as a more accurate adjective for the term CAFO. A quoted Google query for each variant reveals that "concentrated" outnumbers "confined" approximately 6-to-1 in search results.
Traditional organic farmers often oppose the arrival of CAFOs and factory farms in their areas.
by VocabularyGuy June 02, 2006
 
2.
short vertion / australian vertion of saying cathlic club
caf'o
yea mate just been down the cafo
fridy nights at da cafo go off bra
by The Dreadfather November 10, 2007
 
3.
Concentrated (or Confined) Animal Feeding Operation, also known as a 'factory farm'. In industry/government publications, CAFO will usually signify "concentrated". Organic farmers and animal rights advocates prefer "confined" as a more accurate adjective for this term. A quoted Google query for each variant reveals that "concentrated" outnumbers "confined" approximately 6-to-1 in search results.
Traditional organic farmers usually oppose the arrival of CAFOs and factory farms in their areas.
by VocabularyGuy May 30, 2006
 
4.
acronym for" Cold as Fuck outside".
"Man, it's Cafo! i need a jacket."
by Knightunderground February 04, 2010