To ruin a phrase, band, etc. through overuse or chronic misuse. Can also be ruined by a certain person or group using it (Ex. an Ex-girlfriend, posers), or unintentionally mangled (Ex. a friend who can't do a good Mr. Mackey impression to save his life, but insists on doing it over and over because he thinks he's great at it). Sadly, anything can be Brondonized: movies, sexual positions, entire genres of film.
"I can't stand this song anymore. My ex-girlfriend Brondonized it."
"The posers at Hot Topic are trying to Brondonize Iron Maiden. Bastards."