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3.
As heard in the movie "House of Wax", bless me is a term used when asking for alcohol.
- Something's dead out there.
- Nah, something's dead right here, and we have to drink it back to life. Bless me, dog.
by Rose Rampage July 24, 2009
 
1.
A term used when you sneeze and nobody says, "bless you," resulting in the sneezer requiring to bless themselves.
Jesse: "ACHOO!"
Everyone else: .... Silence.....
Jesse: ..... Fine. Bless me. Thanks everyone.
by Hippoblast May 19, 2013
 
2.
"Bless Me" is used jokingly, or not, when asking for sexual favors from a young woman who attends a catholic or parochial school. This is referring to the hookup as a blessing to the guy.
John: Hey katie, want to come over and watch a movie?
Katie: A movie sounds good, but, seriously, you need to stop trying to get into my pants.
John: Oh, it's not your pants, but that cute little uniform I'm interested in. Bless me baby!
Katie: John, you're a pig.
by ThePseudonym22 July 25, 2009