Top Definition
A disorder in which a person has a face that makes you think he/she is a bitch. Said person might not actually be a bitch, but they look like one. BFS can be used for short.
Chris: Wow, that girl has a severe case of Bitch Face Syndrome.
Mandy: Yeah, she looked pissed off for no reason.
by MasterAtNone91 January 20, 2010

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