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When a woman has one breast larger than the other.
Amy is getting a boob job to cure her biggie smalls syndrome.
by El_Karnicero January 31, 2008

Words related to Biggie Smalls Syndrome

biggie smalls boobs breast chichis notorious big senos tetas tits
When one womans breast is larger than the other.
Yo mama got one big titty and one little titty, they call the bitch biggie smalls! - Biggie Smalls syndrome
by Chips and subs November 14, 2010