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1.
The Secretary of Homeland Security -- Janet Napolitano.

A reference to George Orwell’s 1984 ( Big Brother ).
The biggest threat to our freedoms isn't Islamist or domestic terrorists -- it's the Department of Homeland Security and Big Sis!
by Alohacop November 27, 2010
 
2.
A sorority girl who is the mentor of a new sorority (statistic) member. New members zealously love their "big sis", and they usually proclaim their love by window-chalking "I LUV MY BIG SIS!!!" all over their car.
New sorority girl: "I love my big sis!! I love her, I love her, I love her, I love her, I love her..."

New sorority girl's boyfriend: "Uhhh..."
by jvarna5 January 28, 2008
 
3.
well buggered beef attached to an eski lid and thrown into the sea as shark bait, often found washed up on bondi beach asking british backpakers if they want a job
hey man we better thow some big si out there before those white pointers steal all the waiters cloths
by pejax April 28, 2003
 
4.
hugh cans
mmmmmmmmmmmmmmmmmmmmm tiggle bities