The .500 S&W Magnum. Sometimes erroneously attributed to the .50 Action Express, used in the MRI Desert Easgle.
Don't fuck with Hector, He's strappin a big five.
by Wolf89 January 30, 2006
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Pertinent to major negative impacts of the United States governing system; Banker(s), MSM, Corporate Elite(s), Wall Street crook(s), Communist(s) & or most Liberal(s). Although they all intertwine.
Piers Morgan is part of The Big Five.

Notes:
1.Typically generalized as anyone anti-American.
2.Terminology not be used by anyone in The Big Five and an outrage if so.
by Anao344 January 24, 2013
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On a scale from 1 to 5, 5 being most likely, how likely a female is to initiate sex.
Bill: you think I should ask out Jenny?
Larry: Damn right! And come prepared, that girl is a big ol five.
by Caperdude March 1, 2010
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The new five dollar bill. Called the big gay five for the gigantic purple five on the back. A term coined by Andy Parsons.
"Repairing my minivan cost me a whole lot of big gay fives."
by TehHoz April 2, 2008
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variation of high five; used to wish a dude or a bro, good luck or success
"Big fives to ya on your concert tomorrow night, bro'!"
by bongoman October 16, 2007
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