2. (slang) Characterizing harsh, serious treatment.
3. (slang) Sexual. Used in the phrase, "in the Biblical sense", esp. applied to the use of the verb "know".
(def. 3): Yeah, I'm really glad I got to know Lisa. Heh, in the biblical sense.
2: The only adjective in the english language worthy of describing The Big Lebowski
Andy: Biblical win!
Andy: That was some biblical pwnage!