Top Definition
A disease that your best friend inflicts upon you when you have not seen them for at least six months. Symptoms including crying and nagging of your best friend. The only known cure for this disease is for the affected patient to see their best friend. In severe, cases, if left untreated the disease can lead to fighting among best friends.
Dude, I haven't seen my best friend in months! I'm gonna get best friend withdrawal syndrome!
by ballet12 March 28, 2011

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