In reference/salute to Adult Video Star Belladonna, it is slang for the status of a sexually righteous woman comfortable in her sexuality who throws logic to the wind and BECOMES sex and anything goes. When that woman has become the living epitome of raw and over the top sex, where roughness and sensuality collide into a supernova of endless moans and groans and the joys of being human end in eruptions of bliss from both male and female.
Mike: "Man I'm the luckiest man alive."

Nathan: "Why?"

Mike: "Stacy got Belladonna Nasty on me after the concert. I can barely walk from her artistry, and she's not gonna shit right for a week either."
by Mercenary X99 November 16, 2011

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