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1.
To be completely and utterly fucking crazy. It can be used to describe a noun. Mostly used to emphasize the emotional state of a person.
The teacher didn't completely erase the notes on the chalkboard, which caused obsessive-compulsive Isaac to go batshit loco and turn over his desk.

I don't know what the fuck happened, all of the sudden he went batshit loco and shit on the couch!
by Capt. Win October 02, 2007